Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559738 | 0.92 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL5507782 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9626409 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10696786 | 0.76 | HTR6 (0.34) | KDM4EALDH1A1HPGD | |
| SCHEMBL6673792 | 0.74 | CYP1A2 (0.34) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL5736019 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10707395 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10709201 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9636148 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10694326 | 0.70 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993549-A1 | MEDICAMENT FORMULATIONS COMPRISING FLUOROQUINOLONES | Bayer Animal Health GmbH (DE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007101560-A1 | MEDICAMENT FORMULATIONS COMPRISING FLUOROQUINOLONES | BAYER ANIMAL HEALTH GMBH (DE) | 2007-09-13 | — | — | WO | disclosed |