SCHEMBL475948

SCHEMBL475948

CCCC[Si](OC(C)=O)(C(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
FAAH O00519 3/20 0.33
LMNA P02545 2/20 0.33
EPHX1 P07099 3/20 0.32
CA1 P00915 2/20 0.31
CES1 P23141 1/20 0.31
MAPT P10636 1/20 0.31
PAOX Q6QHF9 1/20 0.31
CES2 O00748 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475920 0.92 LMNA (0.39) ALDH1A1FAAHLMNAEPHX1CES1
SCHEMBL6545459 0.92 LMNA (0.39) ALDH1A1FAAHLMNAEPHX1CES1
SCHEMBL703538 0.90 TSHR (0.33)
SCHEMBL707411 0.90 TSHR (0.33)
SCHEMBL703028 0.85 TSHR (0.36) ALDH1A1LMNAMAPT
SCHEMBL2185379 0.83 TSHR (0.44) ALDH1A1LMNA
SCHEMBL475947 0.82 LMNA (0.32) LMNAEPHX1CA1MAPT
SCHEMBL6545875 0.82 LMNA (0.40) ALDH1A1FAAHLMNAEPHX1CES1
SCHEMBL6545187 0.81 LMNA (0.43) ALDH1A1LMNAEPHX1MAPT
SCHEMBL6545810 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2173780-B1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN AS (NO) 2012-05-23 EP disclosed
EP-2294148-B1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN AS (NO) 2012-02-01 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-20110123478-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2011-05-26 US disclosed
EP-2294148-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER Jotun A/S (NO) 2011-03-16 EP disclosed
EP-2173780-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER Jotun A/S (NO) 2010-04-14 EP disclosed
WO-2009149919-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2009-12-17 WO disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed