Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545875 | 0.94 | LMNA (0.40) | LMNAMAPTDGKAMAPK1TSHR | |
| SCHEMBL6546037 | 0.93 | LMNA (0.49) | LMNAMAPTDGKAMAPK1TSHR | |
| SCHEMBL6545739 | 0.87 | LMNA (0.46) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL475948 | 0.81 | ALDH1A1 (0.39) | LMNAMAPTALDH1A1EPHX1 | |
| SCHEMBL475947 | 0.79 | LMNA (0.32) | LMNAMAPTEPHX1 | |
| SCHEMBL2185379 | 0.76 | TSHR (0.44) | LMNATSHRALDH1A1 | |
| SCHEMBL5837982 | 0.75 | TSHR (0.46) | LMNAMAPTMAPK1TSHRALDH1A1 | |
| SCHEMBL3778681 | 0.75 | — | — | |
| SCHEMBL15671163 | 0.75 | LMNA (0.47) | LMNAMAPTDGKAMAPK1TSHR | |
| SCHEMBL6546145 | 0.75 | TSHR (0.44) | LMNAMAPTDGKAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |