Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475920 | 1.00 | LMNA (0.39) | LMNAFAAHEPHX1ALDH1A1CES2 | |
| SCHEMBL475948 | 0.92 | ALDH1A1 (0.39) | LMNAFAAHEPHX1ALDH1A1CES2 | |
| SCHEMBL703538 | 0.90 | TSHR (0.33) | MAPK1 | |
| SCHEMBL707411 | 0.86 | TSHR (0.33) | MAPK1 | |
| SCHEMBL5838116 | 0.84 | TSHR (0.50) | LMNAFAAHEPHX1CES2MAPT | |
| SCHEMBL6545739 | 0.84 | LMNA (0.46) | LMNAFAAHEPHX1ALDH1A1CES2 | |
| SCHEMBL475919 | 0.84 | LMNA (0.38) | LMNAFAAHEPHX1CES2MAPT | |
| SCHEMBL6546037 | 0.82 | LMNA (0.49) | LMNAEPHX1ALDH1A1MAPTMEN1 | |
| SCHEMBL703028 | 0.82 | TSHR (0.36) | LMNAALDH1A1MAPT | |
| SCHEMBL5838180 | 0.80 | TSHR (0.43) | LMNAFAAHEPHX1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |