SCHEMBL476080

SCHEMBL476080

NN1C(=O)c2ccccc2S1(=O)=O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 14/20 0.60
CA2 P00918 6/20 0.60
ELANE P08246 2/20 0.56
CA12 O43570 14/20 0.55
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.49
LMNA P02545 1/20 0.49
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151571 0.78 ELANE (0.78) CA9CA2ELANECA12CYP2D6
SCHEMBL18411793 0.77 CA9 (0.37) CA9CA2ELANECA12LMNA
SCHEMBL11773913 0.76 ELANE (0.58) CA9CA2ELANECA12CYP2D6
SCHEMBL29386930 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL358766 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL358829 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL29165711 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL1779607 0.75 ELANE (0.61) CA9CA2ELANECA12CYP2D6
Saccharin Calcium SCHEMBL29394622 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL29853810 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402652-B2 Baclofen conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C G 2008-07-22 US claimed
US-20060142182-A1 Piracetam and piracetam analog conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-06-29 US claimed
US-20060058221-A1 Baclofen conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-03-16 US claimed
US-20060058219-A1 Aminobutyramide conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-03-16 US claimed
EP-4724590-A1 ADENO-ASSOCIATED VIRUS FORMULATIONS 4D Molecular Therapeutics Inc. (US) 2026-04-15 EP disclosed
US-12553062-B2 AAV compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-02-17 US disclosed
US-20250255862-A1 METHODS OF TREATING HEART FAILURE WITH CARDIAC SARCOMERE ACTIVATORS AMGEN INC. 2025-08-14 US disclosed
US-12295952-B2 Methods of treating heart failure with cardiac sarcomere activators CYTOKINETICS, INC. (US) 2025-05-13 US disclosed
US-12269900-B2 Inhibitors of β integrin-G protein α subunit binding interactions THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-04-08 US disclosed
US-12257277-B2 Adeno-associated virus formulations TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-03-25 US disclosed
EP-4512470-A2 METHODS OF TREATING HEART FAILURE WITH CARDIAC SARCOMERE ACTIVATORS Amgen Inc. (US) 2025-02-26 EP disclosed
US-20250002868-A1 ADENO-ASSOCIATED VIRUS SEPARATION ON A CATION EXCHANGER TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-01-02 US disclosed
US-20060058221-A1 Baclofen conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-03-16 US disclosed
US-20060058221-A1 Baclofen conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-03-16 US disclosed
US-20060058219-A1 Aminobutyramide conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-03-16 US disclosed
US-20060058219-A1 Aminobutyramide conjugate and a pharmaceutical composition for treatment of neuronal disorders MILLER LANDON C 2006-03-16 US disclosed
WO-2006015317-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2006-02-09 WO disclosed
EP-0653438-A2 Oligonucleotide compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-17 EP disclosed
US-4867977-A OF GLUCONIC OR LACTIC ACID, CALCIUM CARBONATE, ORGANIC POLYCARBOXYLIC ACID, TREATMENT OF CALCIUM DEFICIENCY SANDOZ, LTD. (CH) 1989-09-19 US disclosed
US-4135028-A PROCESS FOR FIREPROOFING SYNTHETIC FIBER MATERIALS WITH SULPHONAMIDES CIBA-GEIGY CORPORATION (US) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142182-A1 Piracetam and piracetam analog conjugate and a pharmaceutical composition for treatment of neuronal disorders PRLHR, GIPR, NTSR1 CA9 2430/4885CA2 2824/4885ELANE 1336/4885
US-20250255862-A1 METHODS OF TREATING HEART FAILURE WITH CARDIAC SARCOMERE ACTIVATORS TNNC1, TNNT2, TNNI3 CA9 4613/4885CA2 1212/4885ELANE 1994/4885
US-12295952-B2 Methods of treating heart failure with cardiac sarcomere activators TNNC1, TNNT2, TNNI3 CA9 4613/4885CA2 1212/4885ELANE 1994/4885
US-12553062-B2 AAV compositions PRDM9, H1-10, SLC20A1 CA9 182/4885CA2 2353/4885ELANE 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.