SCHEMBL358829

SCHEMBL358829

O=C1c2ccccc2S(=O)(=O)N1I

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 13/20 0.60
CA2 P00918 6/20 0.60
ELANE P08246 2/20 0.56
CA12 O43570 15/20 0.55
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.49
LMNA P02545 1/20 0.49
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386930 1.00 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL29151571 0.78 ELANE (0.78) CA9CA2ELANECA12CYP2D6
SCHEMBL6958970 0.76 CA12 (0.71) CA9CA2ELANECA12CA1
SCHEMBL29033332 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL358766 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
Saccharin Calcium SCHEMBL29394622 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL1779607 0.75 ELANE (0.61) CA9CA2ELANECA12CYP2D6
SCHEMBL476080 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL29853810 0.75 CA9 (0.60) CA9CA2ELANECA12CYP2D6
SCHEMBL30339085 0.75 CA9 (1.00) CA9CA2ELANECA12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3066081-A2 PROCESS FOR THE PREPARATION OF N-IODOAMIDES Technion Research & Development Foundation Ltd. (IL) 2016-09-14 EP claimed
WO-2015068159-A2 PROCESS FOR THE PREPARATION OF N-IODOAMIDES TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2015-05-14 WO claimed
WO-2024081263-A1 DEPOSITION OF METAL-CONTAINING FILMS LAM RESEARCH CORPORATION (US) 2024-04-18 WO disclosed
EP-4330228-A1 G-ALPHA-S INHIBITORS AND USES THEREOF The Regents of the University of California (US) 2024-03-06 EP disclosed
EP-3674381-B1 ORGANIC OPTICAL MATERIAL JAPAN SCIENCE & TECH AGENCY (JP) 2023-05-10 EP disclosed
WO-2022232142-A1 G-ALPHA-S INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-11-03 WO disclosed
US-20200284946-A1 ORGANIC OPTICAL MATERIAL JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2020-09-10 US disclosed
EP-3674381-A1 ORGANIC OPTICAL MATERIAL Japan Science and Technology Agency (JP) 2020-07-01 EP disclosed
US-20200115353-A1 NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA INVENTIVA (FR) 2020-04-16 US disclosed
CN-108699176-A The manufacturing method of polymer and containing free radical polymerization initiation group compound 大日精化工业株式会社 2018-10-23 CN disclosed
US-9637462-B2 Process for the preparation of N-iodoamides TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2017-05-02 US disclosed
US-8980163-B2 Process for producing plastic bottle ADEKA CORPORATION (JP) 2015-03-17 US disclosed
US-8822516-B2 Process for the preparation of iodides TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2014-09-02 US disclosed
US-8822516-B2 Process for the preparation of iodides TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2014-09-02 US disclosed
EP-2423260-B1 PROCESS FOR PRODUCING PLASTIC BOTTLE ADEKA CORP (JP) 2013-12-04 EP disclosed
US-20130165658-A1 PROCESS FOR THE PREPARATION OF IODIDES TECHNION R&D FOUNDATION LTD. (IL) 2013-06-27 US disclosed
US-20130165658-A1 PROCESS FOR THE PREPARATION OF IODIDES TECHNION R&D FOUNDATION LTD. (IL) 2013-06-27 US disclosed
EP-2423260-A1 PROCESS FOR PRODUCING PLASTIC BOTTLE Adeka Corporation (JP) 2012-02-29 EP disclosed
US-20120013049-A1 PROCESS FOR PRODUCING PLASTIC BOTTLE ADEKA CORPORATION (JP) 2012-01-19 US disclosed
US-6147248-A 4-jod-2[N-(N-alkyl-aminocarbonyl)-aminosulfonyl]-benzoic acid methyl ester and derivatived thereof and method for their production HOECHST SCHERING AGREVO GMBH (DE) 2000-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200284946-A1 ORGANIC OPTICAL MATERIAL SLC43A1, SLCO4C1, SLCO1A2 CA9 1600/4885CA2 2645/4885ELANE 2588/4885
US-20200115353-A1 NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA YAP1, TEAD2, TEAD1 CA9 2285/4885CA2 3185/4885ELANE 3789/4885
US-20130165658-A1 PROCESS FOR THE PREPARATION OF IODIDES NISCH, TPO, HDHD5 CA9 152/4885CA2 1626/4885ELANE 2128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.