Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29830420 | 0.84 | PDK2 (0.46) | PDK2PDCD1CD274ESR1ESR2 | |
| SCHEMBL2909585 | 0.80 | GABRA1 (0.64) | KDM4EMEN1LMNAMAPTKMT2A | |
| SCHEMBL2913117 | 0.77 | ALOX5 (0.51) | — | |
| SCHEMBL10051848 | 0.76 | ESR1 (0.47) | PDK2PDCD1CD274ESR1ESR2 | |
| SCHEMBL4792150 | 0.76 | ALDH1A1 (0.46) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL29616923 | 0.76 | ALDH1A1 (0.46) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL9418403 | 0.75 | GABRA1 (0.56) | PDK2PDCD1CD274KDM4ELMNA | |
| SCHEMBL4762264 | 0.74 | ESR1 (0.41) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL19326650 | 0.73 | SMN1; SMN2 (0.47) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL8889986 | 0.72 | PDCD1 (0.62) | PDK2PDCD1CD274KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008273844-A | NEW FLUORENE COMPOUND HAVING PHENOLIC HYDROXY GROUP AND METHYLOL GROUP AND METHOD FOR PRODUCING THE SAME | OSAKA GAS CO LTD | 2008-11-13 | — | — | JP | disclosed |