Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889986 | 0.86 | PDCD1 (0.62) | GABRA1GABRB2PDCD1CD274APOBEC3G | |
| SCHEMBL196227 | 0.86 | GABRA1 (0.57) | GABRA1GABRB2PDCD1CD274APOBEC3G | |
| SCHEMBL8497184 | 0.85 | PDCD1 (0.52) | GABRA1GABRB2PDCD1CD274APOBEC3G | |
| SCHEMBL23486766 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2PDCD1CD274APOBEC3G | |
| SCHEMBL66634 | 0.79 | LMNA (0.55) | GABRA1GABRB2APOBEC3GLMNAKDM4E | |
| SCHEMBL124524 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2PDCD1CD274APOBEC3G | |
| SCHEMBL16527783 | 0.77 | GABRA1 (0.76) | GABRA1GABRB2PDK2DPP4 | |
| SCHEMBL10321626 | 0.77 | LMNA (0.41) | GABRA1GABRB2PDCD1CD274LMNA | |
| SCHEMBL11648774 | 0.75 | GABRA1 (0.81) | GABRA1GABRB2PDCD1CD274APOBEC3G | |
| SCHEMBL5710254 | 0.75 | HSP90AA1 (0.55) | GABRA1GABRB2APOBEC3GTSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370595-B1 | Binder compositions comprising low molecular weight poly(orthomethylolated)phenolic compound and novolac resin | BORDEN INC (US) | 1994-09-07 | — | — | EP | claimed |
| US-4994505-A | Ester-functional curing agent; bonding sand, refractory or foundry material | BORDEN, INC. (US) | 1991-02-19 | — | — | US | claimed |
| EP-0370595-A2 | Binder compositions comprising low molecular weight poly(orthomethylolated)phenolic compound and novolac resin | Borden, Inc. (US) | 1990-05-30 | — | — | EP | claimed |
| EP-0370595-B1 | Binder compositions comprising low molecular weight poly(orthomethylolated)phenolic compound and novolac resin | BORDEN INC (US) | 1994-09-07 | — | — | EP | disclosed |
| US-4994505-A | Ester-functional curing agent; bonding sand, refractory or foundry material | BORDEN, INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0370595-A2 | Binder compositions comprising low molecular weight poly(orthomethylolated)phenolic compound and novolac resin | Borden, Inc. (US) | 1990-05-30 | — | — | EP | disclosed |