Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023692 | 0.83 | PTGS2 (0.46) | HPGDNPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL17545031 | 0.80 | LMNA (0.62) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL692347 | 0.80 | ALDH1A1 (0.66) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10923011 | 0.79 | HPGD (0.56) | HPGDNPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL7481747 | 0.79 | PTGS2 (0.56) | HPGDNPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL30677293 | 0.79 | HPGD (0.60) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL1128274 | 0.79 | HPGD (0.60) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL9733796 | 0.79 | PTGS2 (0.66) | HPGDNPC1RAB9APTGS2LMNA | |
| SCHEMBL3140037 | 0.79 | HPGD (0.64) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2650229 | 0.79 | POLB (0.72) | HPGDNPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260136-B | Phthalide compound and preparation method thereof | 嘉兴学院 | 2023-08-15 | — | — | CN | claimed |
| CN-115260136-A | Phthalide compound and preparation method thereof | 嘉兴学院 | 2022-11-01 | — | — | CN | claimed |
| CN-103467340-A | Preparation method of 2-[(alkoxyl imine) (phenyl)methyl]benzoic acid derivatives | UNIV TIANJIN | 2013-12-25 | — | — | CN | claimed |
| CN-113735756-B | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-114751882-B | Synthesis method of benzofuran | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115260136-B | Phthalide compound and preparation method thereof | 嘉兴学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-113149868-B | Method for synthesizing axichiral diene compound by trivalent rhodium catalysis | 陕西师范大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115433222-A | Preparation method and application of 2- (gem-difluoropropylene) benzamide compound | 五邑大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-115260136-A | Phthalide compound and preparation method thereof | 嘉兴学院 | 2022-11-01 | — | — | CN | disclosed |
| CN-114751882-A | Synthetic method of benzofuran | 南京工业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-113735756-A | Method for synthesizing chiral 3, 3-disubstituted isoindolinone compound by rhodium catalysis | 陕西师范大学 | 2021-12-03 | — | — | CN | disclosed |
| EP-0942901-B1 | CYCLIC IMINES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-20030032667-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-02-13 | — | — | US | disclosed |
| WO-2002064211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| EP-1182199-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
| CN-1244860-A | Cyclic imines as pesticides | BAYER AG (DE) | 2000-02-16 | — | — | CN | disclosed |
| EP-0942901-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022438-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
| US-4126609-A | AZO DYESTUFF WITH A FIBER-REACTIVE GROUP ATTACHED TO A NAPHTHALENE SULPHONIC ACID COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-21 | — | — | US | disclosed |
| US-4049704-A | AZO REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032667-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | MCCC2, EMC1, GANC | HPGD 2180/4885NPC1 2798/4885RAB9A 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.