SCHEMBL310455

SCHEMBL310455

Nc1ccc(Oc2cccc(C(c3cccc(Oc4ccc(N)cc4)c3)(C(F)(F)F)C(F)(F)F)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
MAPT P10636 3/20 0.61
MITF O75030 1/20 0.61
GAA P10253 1/20 0.61
GFER P55789 1/20 0.61
NLRP1 Q9C000 1/20 0.61
NOD2 Q9HC29 1/20 0.61
MAOA P21397 1/20 0.50
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
NLRP3 Q96P20 1/20 0.46
MAOB P27338 3/20 0.46
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29551212 1.00 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL250124 0.88 MAOB (0.56) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL29360696 0.88 MAOB (0.56) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL9350813 0.87 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL3042025 0.87 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL9742335 0.87 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL3465565 0.87 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL476378 0.86 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL10583295 0.86 MAOB (0.54) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL10823794 0.84 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MAT CO LTD (KR) 2026-04-02 US claimed
EP-4714998-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2026-03-25 EP claimed
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI ADVANCED MAT CO LTD (KR) 2026-03-05 US claimed
US-12522704-B2 Polyimide film having high dimensional stability and manufacturing method therefor PI ADVANCED MATERIALS CO., LTD. (KR) 2026-01-13 US claimed
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR PL ADVANCED MAT CO LTD (KR) 2026-01-08 US claimed
US-12503596-B2 Low-dielectric-constant polyimide composite powder, and method for producing same PI ADVANCED MATERIALS CO., LTD. 2025-12-23 US claimed
EP-4626991-A1 POLYIMIDE VARNISH FOR COATING CONDUCTOR WITH IMPROVED HEAT DISSIPATION FOR COATING CONDUCTOR AND POLYIMIDE COATING MATERIAL COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2025-10-08 EP claimed
EP-1368411-B1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2005-07-06 EP claimed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP claimed
US-20040185215-A1 Photoactive polymer based on polyimides, polyamic acids and esters characterised in that it contains as a side-chain a dendritic block incorporating photoactive groups at its surface; use as orientation layers for liquid crystals and in the construction of unstructured and structured optical elements ROLIC AG (CH) 2004-09-23 US claimed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO claimed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 EP claimed
US-6040418-A FLUORINATED POLYMIDES COMPRISING UNITS OF 2,2',5,5',6,6'-HEXAFLUOROBIPHENYL-3,3',4,4'-TETRACARBOXYLIC DIANHYDRIDE AND AROMATIC DIAMINE UBE INDUSTRIES, LTD. (JP) 2000-03-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PARG, PARN, DYNC1LI1 ALDH1A1 1618/4885SMN1; SMN2 3687/4885MEN1 1369/4885
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF SMURF1, TET1, VCL ALDH1A1 3169/4885SMN1; SMN2 338/4885MEN1 2740/4885
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME AOC1, AOC2, DDT ALDH1A1 40/4885SMN1; SMN2 1919/4885MEN1 1343/4885
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM CDH1, PBRM1, ITGA1 ALDH1A1 228/4885SMN1; SMN2 2173/4885MEN1 2266/4885
US-20260008935-A1 POLYIMIDE FILM AND MANUFACTURING METHOD THEREFOR MALT1, CDH1, TET1 ALDH1A1 1801/4885SMN1; SMN2 2002/4885MEN1 58/4885
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PARG, PARN, PUF60 ALDH1A1 1975/4885SMN1; SMN2 2414/4885MEN1 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.