Cetraxate

Cetraxate

SCHEMBL476429

NCC1CCC(C(=O)Oc2ccc(CCC(=O)O)cc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 1.00
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ELANE P08246 2/20 0.46
FFAR1 O14842 11/20 0.46
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
LMNA P02545 2/20 0.43
FFAR4 Q5NUL3 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PLG P00747 1/20 0.41
PLAT P00750 1/20 0.41
SRD5A2 P31213 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cetraxate SCHEMBL7616457 1.00 F2 (1.00) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL20774010 1.00 F2 (1.00) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL19437 1.00 F2 (1.00) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL11215307 0.99 F2 (0.97) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL10789557 0.99 F2 (0.97) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL11215310 0.99 F2 (0.97) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL144286 0.99 F2 (0.97) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL144285 0.99 F2 (0.97) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL4639111 0.99 F2 (0.97) F2HTTKMT2ASMN1; SMN2TDP1
Cetraxate SCHEMBL1649792 0.97 F2 (0.95) F2HTTKMT2ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220330541-A1 Methods for the Preservation of Reagent Red Blood Cells Using Carbon Monoxide HEMANEXT INC. (US) 2022-10-20 US claimed
US-11136342-B2 Carbonate prodrugs and methods of using the same ACORDA THERAPEUTICS, INC. (US) 2021-10-05 US claimed
US-20200157126-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME ACORDA THERAPEUTICS, INC. 2020-05-21 US claimed
US-20150328323-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents SATYAM APPARAO (IN) 2015-11-19 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
WO-2014111957-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS SATYAM APPARAO (IN) 2014-07-24 WO claimed
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
WO-2011132171-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 WO claimed
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 US claimed
US-20110212927-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME NEUROGESX, INC. (US) 2011-09-01 US claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061541-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061537-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5908824-A DISPERSED HOMOGENEOUSLY IN AND ADSORBED HOMOGENEOUSLY ONTO A MUCOSA PROTECTING AND/OR TISSUE REPAIRING AGENT DOTT RESEARCH LABORATORY (JP) 1999-06-01 US claimed
WO-1998022114-A1 A METHOD FOR PROMOTING TISSUE REPAIR DUMEX-ALPHARMA A/S (DK) 1998-05-28 WO claimed
EP-0580860-B1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 1997-10-22 EP claimed
EP-0770390-A1 Nasally administrable compositions containing physiologically active peptides DOTT RESEARCH LABORATORY (JP) 1997-05-02 EP claimed
EP-0591546-A1 EXTERNAL PREPARATION FOR CURING DAMAGE TO SKIN DOTT LIMITED COMPANY (JP) 1994-04-13 EP claimed
US-4147876-A CHEMICAL INTERMEDIATE FOR ANTIULCER AGENTS AND ENZYME INHIBITORS DAIICHI SEIYAKU CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212927-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 F2 3207/4885HTT 4037/4885KMT2A 2173/4885
US-20200157126-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 F2 3207/4885HTT 4037/4885KMT2A 2173/4885
US-11136342-B2 Carbonate prodrugs and methods of using the same CA6, CA7, CA4 F2 3207/4885HTT 4037/4885KMT2A 2173/4885
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents NOS2, NOS1, NOS3 F2 1609/4885HTT 4296/4885KMT2A 3867/4885
US-20150328323-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents NOS2, NOS1, PTGIS F2 2360/4885HTT 2769/4885KMT2A 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.