Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 8/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4120239 | 0.92 | HTR6 (0.40) | NAMPTHTR6ALDH1A1L3MBTL1 | |
| SCHEMBL4126131 | 0.92 | HTT (0.37) | NAMPTHTTATMALDH1A1L3MBTL1 | |
| SCHEMBL18258908 | 0.90 | NAMPT (0.35) | NAMPTHTR6HTTATMALDH1A1 | |
| SCHEMBL4125767 | 0.90 | NFE2L2 (0.39) | NAMPT | |
| SCHEMBL476390 | 0.88 | HTT (0.39) | NAMPTHTTALDH1A1 | |
| SCHEMBL476366 | 0.88 | NAMPT (0.38) | NAMPTALDH1A1L3MBTL1 | |
| SCHEMBL476363 | 0.86 | HTR6 (0.39) | NAMPTHTR6ALDH1A1L3MBTL1GRM4 | |
| SCHEMBL476470 | 0.84 | HTR6 (0.36) | NAMPTHTR6ALDH1A1L3MBTL1GRM4 | |
| SCHEMBL476445 | 0.84 | HTR6 (0.38) | NAMPTHTR6GRM4 | |
| Hydrochloric Acid SCHEMBL476331 | 0.83 | HTR6 (0.38) | NAMPTHTR6GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412713-B1 | PYRAZOLE COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2016-11-30 | — | — | EP | disclosed |
| EP-2412713-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-02-01 | — | — | EP | disclosed |