Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126131 | 0.92 | HTT (0.37) | NAMPTALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL476471 | 0.92 | NAMPT (0.35) | HTR6NAMPTALDH1A1L3MBTL1 | |
| SCHEMBL18258908 | 0.91 | NAMPT (0.35) | HTR6NAMPTHTR7ALDH1A1L3MBTL1 | |
| SCHEMBL476390 | 0.91 | HTT (0.39) | NAMPTALDH1A1PTGDR2 | |
| SCHEMBL476366 | 0.89 | NAMPT (0.38) | NAMPTALDH1A1L3MBTL1 | |
| SCHEMBL4125767 | 0.89 | NFE2L2 (0.39) | NAMPTNFE2L2PTGDR2 | |
| SCHEMBL3702686 | 0.82 | HTR6 (0.40) | HTR6HTR2AHTR2CHTR7NFE2L2 | |
| Hydrochloric Acid SCHEMBL3703128 | 0.81 | HTR6 (0.46) | HTR6HTR2AHTR2CHTR7NFE2L2 | |
| SCHEMBL4135836 | 0.81 | HTT (0.37) | NAMPTALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL4127066 | 0.80 | EPHX2 (0.36) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | HTR6 3676/4885NAMPT 2129/4885HTR2A 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.