Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841290 | 0.84 | ALDH1A1 (0.47) | MGLLLMNAALDH1A1 | |
| SCHEMBL4724233 | 0.83 | HPGD (0.54) | HTR2BLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL3860311 | 0.83 | ALDH1A1 (0.47) | MGLLLMNAALDH1A1 | |
| SCHEMBL4764354 | 0.83 | POLB (0.41) | LMNAALDH1A1 | |
| SCHEMBL2884746 | 0.81 | HRH3 (0.51) | MGLL | |
| SCHEMBL4889725 | 0.81 | KCNH2 (0.42) | ALDH1A1 | |
| SCHEMBL3797395 | 0.80 | HRH3 (0.46) | LMNAKDM4EALDH1A1 | |
| SCHEMBL2879390 | 0.79 | RECQL (0.42) | KDM4EALDH1A1 | |
| SCHEMBL4793576 | 0.79 | MEN1 (0.40) | ALDH1A1 | |
| SCHEMBL4791508 | 0.79 | LMNA (0.42) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | disclosed |