Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889725 | 0.93 | KCNH2 (0.42) | DRD2TBXA2RKCNH2AGTR1AGTR2 | |
| SCHEMBL4764354 | 0.92 | POLB (0.41) | MEN1KMT2AALDH1A1RECQLMAPT | |
| SCHEMBL4790935 | 0.91 | DRD2 (0.42) | KMT2ADRD2TBXA2RKCNH2CNR2 | |
| SCHEMBL4791508 | 0.89 | LMNA (0.42) | MEN1KMT2ADRD2TBXA2RKCNH2 | |
| SCHEMBL4764592 | 0.83 | HRH3 (0.54) | KCNH2 | |
| SCHEMBL4792764 | 0.80 | ADAM17 (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL4765934 | 0.79 | MGLL (0.40) | ALDH1A1 | |
| SCHEMBL4724233 | 0.78 | HPGD (0.54) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4161023 | 0.77 | HRH3 (0.52) | KCNH2 | |
| SCHEMBL4793698 | 0.77 | KCNH2 (0.39) | MEN1KMT2AKCNH2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | disclosed |