Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694578 | 0.77 | TAAR1 (0.52) | — | |
| SCHEMBL7425678 | 0.77 | ALDH1A1 (0.55) | SLC16A3ALDH1A1 | |
| SCHEMBL4767312 | 0.76 | MCOLN3 (0.55) | PGR | |
| SCHEMBL4772836 | 0.74 | ALDH1A1 (0.51) | SLC16A3ALDH1A1 | |
| SCHEMBL30861873 | 0.73 | HDAC3 (0.57) | ALDH1A1 | |
| SCHEMBL2316238 | 0.73 | HDAC3 (0.57) | ALDH1A1 | |
| SCHEMBL12916500 | 0.73 | FABP4 (0.51) | PTGES2PGRALDH1A1ITGAV | |
| SCHEMBL5846778 | 0.72 | TAAR1 (0.50) | — | |
| SCHEMBL3897238 | 0.72 | KEAP1 (0.55) | SLC16A3ALDH1A1 | |
| SCHEMBL3775622 | 0.72 | PTGES2 (1.00) | PTGES2SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |