Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736525 | 0.85 | MEN1 (0.43) | KDM4ENPSR1FAAHMGLLELANE | |
| SCHEMBL2115731 | 0.76 | GAA (0.58) | KDM4ENPSR1 | |
| SCHEMBL2301149 | 0.73 | ELANE (0.39) | KDM4ENPSR1RXFP1ELANE | |
| SCHEMBL2302376 | 0.72 | ELANE (0.39) | KDM4ENPSR1RXFP1ELANE | |
| SCHEMBL7344853 | 0.70 | F12 (0.34) | GRM2 | |
| SCHEMBL31602785 | 0.69 | ALDH1A1 (0.46) | KDM4ERXFP1 | |
| SCHEMBL23071596 | 0.68 | KDM4E (0.42) | KDM4ENPSR1RXFP1ELANE | |
| SCHEMBL9987666 | 0.68 | ELANE (0.55) | ELANE | |
| SCHEMBL9994966 | 0.68 | FAAH (0.40) | GRM2KDM4EFAAH | |
| SCHEMBL19911637 | 0.68 | GRM2 (0.62) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2410857-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | Merck Sharp & Dohme Corp. (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111058-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |