Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767519 | 0.89 | P4HTM (0.42) | P4HTMHTTSMN1; SMN2POLBCCKAR | |
| SCHEMBL4773852 | 0.86 | PPARG (0.41) | P4HTMLMNASMN1; SMN2GRM8GRM4 | |
| SCHEMBL4771490 | 0.84 | CYP2C9 (0.40) | LMNAPOLB | |
| SCHEMBL4764854 | 0.82 | CCKAR (0.45) | POLBAKR1C3AKR1C2CCKAR | |
| SCHEMBL4773748 | 0.78 | KMT2A (0.35) | P4HTMCPB2SMN1; SMN2 | |
| SCHEMBL4770006 | 0.77 | NFKB1 (0.47) | AKR1C3AKR1C2 | |
| SCHEMBL4769975 | 0.77 | ATF1 (0.39) | AKR1C3AKR1C2CCKAR | |
| SCHEMBL4775298 | 0.77 | ACHE (0.41) | LMNASMN1; SMN2POLBAKR1C3AKR1C2 | |
| SCHEMBL4768165 | 0.75 | CTSA (0.38) | P4HTMCPB2SMN1; SMN2ROCK2 | |
| SCHEMBL4767426 | 0.75 | KMT2A (0.41) | LMNASMN1; SMN2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581531-B1 | PYRIDINO¬2,3-D PYRIMIDINE DERIVATIVES AS SELECTIIVE KDR AND FGFR INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-02-27 | — | — | EP | claimed |