SCHEMBL4768280

SCHEMBL4768280

O=C(Nc1ccccc1)OB(OC(=O)Nc1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.50
ALDH1A1 P00352 2/20 0.50
GAA P10253 2/20 0.50
HTT P42858 1/20 0.50
TSHR P16473 2/20 0.48
TP53 P04637 2/20 0.48
EPHX1 P07099 1/20 0.48
EPHX2 P34913 1/20 0.48
CDK9 P50750 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48
NAPRT Q6XQN6 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RAB9A P51151 4/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
NPC1 O15118 2/20 0.45
MAPT P10636 1/20 0.45
RECQL P46063 1/20 0.44
HPGD P15428 1/20 0.43
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5785644 0.83 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1GAAHTTTSHR
SCHEMBL2244779 0.74 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1GAAHTTTSHR
SCHEMBL918997 0.74 ORAI1 (0.42) SMN1; SMN2ALDH1A1TSHRNAPRTHSD17B10
SCHEMBL8827353 0.74 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1GAAHTTTSHR
SCHEMBL9326 0.73 RAB9A (0.49) SMN1; SMN2ALDH1A1GAATSHREPHX1
SCHEMBL8612411 0.73 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1GAAHTTTSHR
SCHEMBL282531 0.73 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1GAAHTTTSHR
SCHEMBL5778129 0.72 KMT2A (0.44) SMN1; SMN2ALDH1A1GAAHTTTSHR
SCHEMBL1490892 0.72 POLB (0.40) GAAHTTTSHREPHX1RAB9A
SCHEMBL5564047 0.71 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1GAAHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113728070-B Ultraviolet absorber excellent in heat resistance and long-wavelength absorption 三吉油脂株式会社 2024-03-08 CN disclosed
CN-113728070-A Ultraviolet absorber having excellent heat resistance and excellent long-wavelength absorption 三吉油脂株式会社 2021-11-30 CN disclosed
WO-2020218609-A1 ULTRAVIOLET ABSORBER HAVING EXCELLENT HEAT RESISTANCE AND LONG-WAVELENGTH ABSORPTION ミヨシ油脂株式会社 2020-10-29 WO disclosed
EP-1979353-A2 FUSED HETEROBICYCLIC KINASE INHIBITORS OSI Pharmaceuticals, Inc. (US) 2008-10-15 EP disclosed
WO-2007084667-A2 FUSED HETEROBICYCLIC KINASE INHIBITORS OSI PHARMACEUTICAL, INC. (US) 2007-07-26 WO disclosed