SCHEMBL918997

SCHEMBL918997

O=C(O)OB(OC(=O)O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 3/20 0.42
ORAI2 Q96SN7 3/20 0.42
ORAI3 Q9BRQ5 3/20 0.42
TRPV6 Q9H1D0 3/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA7 P43166 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
ENPP2 Q13822 1/20 0.42
PCSK9 Q8NBP7 1/20 0.42
F2 P00734 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 4/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 2/20 0.36
DAO P14920 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13581718 0.87 TRPV6 (0.36) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL9621660 0.81 ALDH1A1 (0.44) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL384013 0.81 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL13857742 0.80 GSR (0.34) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL1672441 0.78 ORAI1 (0.46) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL5778129 0.78 KMT2A (0.44) TSHRCES2CES1ALDH1A1NAPRT
SCHEMBL1712461 0.76 ELANE (0.46) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL28565346 0.76 TRPV6 (0.48) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL28946497 0.75 CA4 (0.38) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL4768280 0.74 SMN1; SMN2 (0.50) LMNATSHRALDH1A1NAPRTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115851267-B Double-emission room-temperature phosphorescent material and preparation method and application thereof 武汉大学 2024-10-08 CN claimed
CN-115851267-A Dual-emission room temperature phosphorescent material and preparation method and application thereof 武汉大学 2023-03-28 CN claimed
US-10119933-B2 Analysis and assay of glycated haemoglobins by capillary electrophoresis, buffer compositions and kits for capillary electrophoresis SEBIA (FR) 2018-11-06 US claimed
US-20160077052-A1 ANALYSIS AND ASSAY OF GLYCATED HAEMOGLOBINS BY CAPILLARY ELECTROPHORESIS, BUFFER COMPOSITIONS AND KITS FOR CAPILLARY ELECTROPHORESIS SEBIA (FR) 2016-03-17 US claimed
US-9222913-B2 Analysis and assay of glycated haemoglobins by capillary electrophoresis, buffer compositions and kits for capillary electrophoresis SEBIA (FR) 2015-12-29 US claimed
US-20110000788-A1 ANALYSIS AND ASSAY OF GLYCATED HAEMOGLOBINS BY CAPILLARY ELECTROPHORESIS, BUFFER COMPOSITIONS AND KITS FOR CAPILLARY ELECTROPHORESIS SEBIA (FR) 2011-01-06 US claimed
CN-115851267-B Double-emission room-temperature phosphorescent material and preparation method and application thereof 武汉大学 2024-10-08 CN disclosed
CN-115851267-A Dual-emission room temperature phosphorescent material and preparation method and application thereof 武汉大学 2023-03-28 CN disclosed
CN-113121835-B Iron-based metal organic framework material and preparation and application thereof 华东师范大学 2022-07-26 CN disclosed
CN-113121835-A Iron-based metal organic framework material and preparation and application thereof 华东师范大学 2021-07-16 CN disclosed
US-10119933-B2 Analysis and assay of glycated haemoglobins by capillary electrophoresis, buffer compositions and kits for capillary electrophoresis SEBIA (FR) 2018-11-06 US disclosed
CN-106040202-A Borono benzoylated beta-cyclodextrin bonded silica gel and uses thereof 南昌大学 2016-10-26 CN disclosed
US-20160077052-A1 ANALYSIS AND ASSAY OF GLYCATED HAEMOGLOBINS BY CAPILLARY ELECTROPHORESIS, BUFFER COMPOSITIONS AND KITS FOR CAPILLARY ELECTROPHORESIS SEBIA (FR) 2016-03-17 US disclosed
US-9222913-B2 Analysis and assay of glycated haemoglobins by capillary electrophoresis, buffer compositions and kits for capillary electrophoresis SEBIA (FR) 2015-12-29 US disclosed
US-20110000788-A1 ANALYSIS AND ASSAY OF GLYCATED HAEMOGLOBINS BY CAPILLARY ELECTROPHORESIS, BUFFER COMPOSITIONS AND KITS FOR CAPILLARY ELECTROPHORESIS SEBIA (FR) 2011-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110000788-A1 ANALYSIS AND ASSAY OF GLYCATED HAEMOGLOBINS BY CAPILLARY ELECTROPHORESIS, BUFFER COMPOSITIONS AND KITS FOR CAPILLARY ELECTROPHORESIS HBB, HBG1, HBG2 ORAI1 2594/4885ORAI2 3770/4885ORAI3 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.