Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773051 | 0.95 | MAPT (0.56) | MAPTNR1H4WNT3ARAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4768193 | 0.93 | MAPT (0.45) | MAPTNR1H4SLC2A1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4768830 | 0.90 | SLC2A1 (0.43) | MAPTNR1H4SLC2A1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4766836 | 0.89 | SLC2A1 (0.44) | SLC2A1RAB9ANPC1LMNAALDH1A1 | |
| SCHEMBL4767430 | 0.88 | MAPT (0.47) | MAPTNR1H4RAB9ANPC1HPGD | |
| Trifluoroacetic Acid SCHEMBL4768481 | 0.86 | NPY5R (0.49) | SLC2A1HRH3 | |
| Trifluoroacetic Acid SCHEMBL4775487 | 0.86 | KMT2A (0.53) | SLC2A1HPGDLMNAALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4764992 | 0.86 | TP53 (0.51) | MAPTSLC2A1LMNAALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4765180 | 0.84 | POLB (0.52) | MAPTSLC2A1RAB9ANPC1LMNA | |
| Trifluoroacetic Acid SCHEMBL4765747 | 0.83 | MET (0.46) | MAPTSLC2A1ALDH1A1SMN1; SMN2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | claimed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | MAPT 405/4885NR1H4 550/4885SLC2A1 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.