Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768299 | 0.95 | KMT2A (0.59) | KMT2ATSHRF10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL4768481 | 0.86 | NPY5R (0.49) | SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL4774586 | 0.86 | MAPT (0.51) | KMT2ASLC2A1ALDH1A1LMNAHPGD | |
| Trifluoroacetic Acid SCHEMBL4771967 | 0.86 | SLC2A1 (0.45) | KMT2AF10F2PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL4774899 | 0.85 | SLC2A1 (0.43) | KMT2ASLC2A1SMYD3MEN1 | |
| Trifluoroacetic Acid SCHEMBL4764992 | 0.85 | TP53 (0.51) | KMT2ASLC2A1ALDH1A1LMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL4765180 | 0.82 | POLB (0.52) | KMT2ASLC2A1ALDH1A1LMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL4771045 | 0.82 | RAB9A (0.53) | KMT2ASLC2A1HPGDMEN1 | |
| Trifluoroacetic Acid SCHEMBL4772218 | 0.81 | SLC2A1 (0.42) | SLC2A1 | |
| SCHEMBL4767967 | 0.81 | HRH3 (0.48) | KMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | claimed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | KMT2A 99/4885TSHR 1747/4885F10 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.