Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.55 |
| ▸ | FLT3 | P36888 | 10/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.52 |
| ▸ | RAC1 | P63000 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4775088 | 0.95 | MAP4K1 (0.52) | MAP4K1SYKTYRO3CSNK2A1FLT3 | |
| SCHEMBL4772757 | 0.81 | HRH3 (0.52) | NPC1RAB9AACKR3 | |
| SCHEMBL4770359 | 0.78 | ALDH1A1 (0.51) | CHRNA7NPC1RAB9A | |
| SCHEMBL4772503 | 0.78 | MEN1 (0.45) | NPC1RAB9A | |
| SCHEMBL4765386 | 0.78 | TP53 (0.55) | NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4768284 | 0.78 | HRH3 (0.46) | NPC1RAB9AACKR3 | |
| SCHEMBL4768583 | 0.78 | TMPRSS2 (0.62) | NPC1RAB9AACKR3 | |
| SCHEMBL5823896 | 0.77 | HRH3 (0.54) | NPC1RAB9A | |
| SCHEMBL4765564 | 0.77 | HRH3 (0.46) | NPC1RAB9A | |
| SCHEMBL4771101 | 0.76 | HRH3 (0.44) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |