Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4769820 | 0.94 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTROCK2CHRNA7 | |
| SCHEMBL4775002 | 0.81 | RAB9A (0.53) | MAPTHRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4794145 | 0.80 | MAPT (0.53) | ALDH1A1LMNAMAPTHRH3MEN1 | |
| SCHEMBL4770985 | 0.78 | MAP4K1 (0.57) | CHRNA7NPC1RAB9A | |
| SCHEMBL4793943 | 0.78 | ABCB1 (0.55) | MAPTHRH3MEN1KMT2ANPC1 | |
| SCHEMBL4770147 | 0.78 | HRH3 (0.46) | ALDH1A1LMNAMAPTROCK2HRH3 | |
| SCHEMBL5823896 | 0.77 | HRH3 (0.54) | ALDH1A1LMNAMAPTHRH3KMT2A | |
| SCHEMBL4772757 | 0.77 | HRH3 (0.52) | LMNAMAPTHRH3MEN1KMT2A | |
| SCHEMBL4772503 | 0.77 | MEN1 (0.45) | HRH3USP2MEN1KMT2ANPC1 | |
| SCHEMBL4774628 | 0.76 | TMPRSS2 (0.61) | ALDH1A1MAPTHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |