Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774185 | 0.80 | FFAR4 (0.32) | — | |
| SCHEMBL4779864 | 0.68 | NOX1 (0.41) | MAOAMAOB | |
| SCHEMBL4774067 | 0.66 | RXRA (0.44) | — | |
| SCHEMBL4777353 | 0.63 | MAOA (0.37) | TLR9MAOAMAOB | |
| SCHEMBL4879715 | 0.62 | PIM1 (0.44) | — | |
| SCHEMBL4778982 | 0.61 | PSEN1 (0.36) | MAOAMAOB | |
| SCHEMBL4780752 | 0.59 | NPC1 (0.44) | — | |
| SCHEMBL10097344 | 0.57 | MAOA (0.51) | MAOAMAOB | |
| SCHEMBL10251769 | 0.56 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL10097345 | 0.56 | MAOA (0.50) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984332-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |