Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779864 | 0.88 | NOX1 (0.41) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4879715 | 0.80 | PIM1 (0.44) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL8590356 | 0.78 | TUBB4A (0.48) | CYP1A2CYP2C19KDM4EMEN1MAPT | |
| SCHEMBL8589109 | 0.74 | NOX1 (0.46) | CYP1A2CYP2C19KDM4EMEN1MAPT | |
| SCHEMBL4778723 | 0.68 | ALDH1A1 (0.33) | CYP1A2CYP2C19KDM4EMEN1MAPT | |
| SCHEMBL2997363 | 0.67 | SRD5A2 (0.63) | RXRACYP1A2CYP2C19KDM4EMEN1 | |
| SCHEMBL10097356 | 0.64 | ALDH1A1 (0.53) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL20068149 | 0.64 | ACMSD (0.67) | CHEK2POLB | |
| SCHEMBL2035502 | 0.64 | RXRA (1.00) | RXRAKDM4ERXRBCA1CA2 | |
| SCHEMBL10097344 | 0.63 | MAOA (0.51) | CYP1A2KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979315-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |