Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771892 | 0.80 | TLR9 (0.31) | — | |
| SCHEMBL4776654 | 0.78 | PDE10A (0.36) | PDE2ADHODHPDE4BPDE10A | |
| SCHEMBL4773204 | 0.77 | CHEK2 (0.38) | PDE2ADHODHPDE4BPDE10A | |
| SCHEMBL4779864 | 0.68 | NOX1 (0.41) | PDE10A | |
| SCHEMBL4778982 | 0.63 | PSEN1 (0.36) | — | |
| SCHEMBL4879715 | 0.62 | PIM1 (0.44) | — | |
| SCHEMBL4776292 | 0.62 | PDE10A (0.38) | PDE10A | |
| SCHEMBL10095976 | 0.60 | TRPA1 (0.40) | PDE2ADHODHPDE4BPDE10A | |
| SCHEMBL10591159 | 0.58 | ADORA1 (0.39) | PDE2ADHODHPDE4BPDE10A | |
| SCHEMBL10591906 | 0.56 | DHODH (0.40) | PDE2ADHODHPDE4BPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984332-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1979315-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |