Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320052 | 0.85 | HTR2A (0.34) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL29405961 | 0.84 | ALDH1A1 (0.40) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL19017672 | 0.84 | ALDH1A1 (0.40) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL4943541 | 0.84 | ALDH1A1 (0.40) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL31245687 | 0.82 | ATM (0.37) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL5697727 | 0.82 | NOTUM (0.37) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL642506 | 0.82 | ATM (0.37) | HTR2AKDM4EALDH1A1POLBATM | |
| SCHEMBL1025069 | 0.81 | ATM (0.40) | ALDH1A1POLBATMMAPT | |
| SCHEMBL22812324 | 0.74 | BRD4 (0.36) | ALDH1A1MAPTBRD4 | |
| SCHEMBL28386874 | 0.74 | SLC25A5 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |