Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405961 | 0.87 | ALDH1A1 (0.40) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL4943541 | 0.87 | ALDH1A1 (0.40) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL19017672 | 0.87 | ALDH1A1 (0.40) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL5697727 | 0.85 | NOTUM (0.37) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL31245687 | 0.85 | ATM (0.37) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL4772652 | 0.85 | HTR2A (0.32) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL642506 | 0.85 | ATM (0.37) | HTR2AALDH1A1ATMCYP2D6KDM4E | |
| SCHEMBL1025069 | 0.84 | ATM (0.40) | ALDH1A1ATMPOLBMAPT | |
| SCHEMBL22812324 | 0.77 | BRD4 (0.36) | ALDH1A1MAPTBRD4TDP1 | |
| SCHEMBL28386874 | 0.77 | SLC25A5 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649035-B | Pentakis/hexamethyl-3, 4,5, 8-tetrahydro-1 (2H) -naphthalenone derivatives with aromatic notes | FIRMENICH & CIE | 2015-04-15 | — | — | CN | disclosed |
| EP-1855548-A2 | MOLECULES COMPRISING LINKED ORGANIC MOIETIES AS FLAVOR MODIFIERS FOR COMESTIBLES COMPOSITIONS | Senomyx, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060257543-A1 | Molecules comprising linked organic moieties as flavor modifiers for comestible compositions | SENOMYX, INC. | 2006-11-16 | — | — | US | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006084184-A2 | MOLECULES COMPRISING LINKED ORGANIC MOIETIES AS FLAVOR MODIFIERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| CN-1360890-A | Use of active retiene derivative with negative hormone and/or antagonist | ALLERGAN INC (US) | 2002-07-31 | — | — | CN | disclosed |