Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405961 | 1.00 | ALDH1A1 (0.40) | ALDH1A1EDNRATDP1ATMHSPA1A | |
| SCHEMBL19017672 | 1.00 | ALDH1A1 (0.40) | ALDH1A1EDNRATDP1ATMHSPA1A | |
| SCHEMBL5320052 | 0.87 | HTR2A (0.34) | ALDH1A1TDP1ATMHSPA1APTPN7 | |
| SCHEMBL1025069 | 0.86 | ATM (0.40) | ALDH1A1ATMPOLBTSHR | |
| 4-Hydroxybenzaldehyde SCHEMBL28936869 | 0.85 | ALDH5A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL642506 | 0.84 | ATM (0.37) | ALDH1A1ATMPOLBHTR2ATSHR | |
| SCHEMBL4772652 | 0.84 | HTR2A (0.32) | ALDH1A1ATMPOLBPTGDR2HTR2A | |
| SCHEMBL5697727 | 0.84 | NOTUM (0.37) | ALDH1A1ATMPOLBHTR2ATSHR | |
| SCHEMBL31245687 | 0.84 | ATM (0.37) | ALDH1A1ATMPOLBHTR2ATSHR | |
| SCHEMBL29053325 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149360-A1 | BIQUATERNARY AMMONIUM SALT COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF | 西藏海思科制药有限公司 | 2024-07-18 | — | — | WO | claimed |
| CN-117417338-A | Novel BRD4 protein targeted degradation agent, and preparation method and application thereof | 中国药科大学 | 2024-01-19 | — | — | CN | claimed |
| US-20230416258-A1 | BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-12-28 | — | — | US | claimed |
| EP-4242210-A1 | NEW BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | China Pharmaceutical University (CN) | 2023-09-13 | — | — | EP | claimed |
| CN-116253652-A | Long-chain fatty acid ester derivative, pharmaceutically acceptable salt and pharmaceutical composition of tapentadol, and preparation method and application thereof | 武汉思瓴生物科技有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-114456171-A | Benzodiazepine medicine for sedation and hypnosis, preparation method and application thereof | 中国药科大学 | 2022-05-10 | — | — | CN | claimed |
| CN-112358483-A | Novel benzodiazepine compound, preparation method and application thereof | 中国药科大学 | 2021-02-12 | — | — | CN | claimed |
| CN-119365467-A | Aza-tetraepoxy aza compounds and uses thereof | 基因泰克公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119192183-A | Benzodiazepines class of compounds and uses thereof | 中国药科大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-119183377-A | Methods and compositions comprising an SHP2 inhibitor and a PD-L1 binding antagonist | 基因泰克公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-119013026-A | Combination therapy comprising GDC-6036 and GDC-0077 for the treatment of cancer | 基因泰克公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118891064-A | Conjugation methods involving transglutaminase at FC-regions comprising trimmed N-glycans | ADC治疗有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118510782-A | As CaV1.2 Pyridine-3-carboxylic acid ester Compounds of activators | 诺华股份有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-4764635-A | Aromatization process | ETHYL CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| US-4762943-A | Aromatization process | ETHYL CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0256849-A1 | Aromatization process | ETHYL CORPORATION (US) | 1988-02-24 | — | — | EP | disclosed |
| EP-0254422-A1 | Aromatization process | ETHYL CORPORATION (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0010842-B1 | POLYURETHANE FOAM AND METHOD OF PREPARATION THEREOF | UNIROYAL LTD. (CA) | 1983-09-21 | — | — | EP | disclosed |
| US-4209593-A | Semi-flexible shock-absorbing polyurethane foam prepared from a triol, a compound having a single reactive hydrogen, an aromatic polyisocyanate, blowing agent, chain-extender and a catalyst | UNIROYAL LTD. (CA) | 1980-06-24 | — | — | US | disclosed |
| EP-0010842-A1 | Polyurethane foam and method of preparation thereof | UNIROYAL LTD. (CA) | 1980-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416258-A1 | BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | GABRA4, GABRA1, GABRA5 | ALDH1A1 1744/4885EDNRA 3496/4885TDP1 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.