Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD3 | P35462 | 3/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.62 |
| ▸ | HTR7 | P34969 | 4/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949387 | 0.89 | DRD2 (0.79) | KDM4EDRD2DRD3DRD4HTR1A | |
| SCHEMBL4775148 | 0.88 | DRD2 (0.62) | KDM4ETSHRDRD2DRD3DRD4 | |
| SCHEMBL947201 | 0.82 | HTR1A (0.69) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL19140382 | 0.82 | HTR1A (0.65) | KDM4EDRD2DRD3DRD4HTR1A | |
| SCHEMBL4753124 | 0.82 | KDM4E (0.81) | KDM4ETSHRDRD2DRD3DRD4 | |
| SCHEMBL5172365 | 0.82 | HTR2A (0.74) | TSHRDRD2DRD3DRD4HTR1A | |
| SCHEMBL946686 | 0.82 | LMNA (0.59) | TSHRDRD2DRD3DRD4HTR1A | |
| SCHEMBL20629330 | 0.81 | DRD2 (0.60) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL5198374 | 0.80 | DRD3 (0.68) | KDM4EDRD2DRD3DRD4HTR1A | |
| SCHEMBL17533456 | 0.80 | HTR1A (0.62) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |