Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772742 | 1.00 | SIGMAR1 (0.41) | SIGMAR1OPRM1OPRD1CA12CA1 | |
| SCHEMBL82429 | 0.89 | KMT2A (0.43) | SIGMAR1OPRM1CA12CA1CA7 | |
| SCHEMBL740806 | 0.81 | POLB (0.39) | SIGMAR1OPRM1OPRD1CA12CA1 | |
| SCHEMBL739535 | 0.78 | SIGMAR1 (0.47) | SIGMAR1OPRM1OPRD1CA12CA1 | |
| SCHEMBL4775252 | 0.78 | SIGMAR1 (0.47) | SIGMAR1OPRM1OPRD1CA12CA1 | |
| SCHEMBL4772735 | 0.75 | KMT2A (0.39) | CTSSCTSKATMKMT2AMAPT | |
| SCHEMBL740952 | 0.74 | BDKRB2 (0.43) | SIGMAR1OPRM1OPRD1KMT2APOLB | |
| SCHEMBL739715 | 0.71 | SIGMAR1 (0.44) | SIGMAR1OPRM1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL13201400 | 0.71 | OPRD1 (0.49) | SIGMAR1OPRM1OPRD1CA12CA1 | |
| SCHEMBL81713 | 0.71 | NPFFR1 (0.50) | SIGMAR1OPRD1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930321-A1 | PROCESS FOR PREPARATION OF TETRASUBSTITUTED 5-AZASPIRO[2.4]- HEPTANE DERIVATIVES AND OPTICALLY ACTIVE INTERMEDIATES THEREOF | Daiichi Sankyo Company, Limited (JP) | 2008-06-11 | — | — | EP | claimed |