Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694641 | 1.00 | LIPE (0.44) | LIPEL3MBTL1HPGDGAACTSK | |
| SCHEMBL477283 | 0.98 | LIPE (0.42) | LIPEL3MBTL1HPGDGAACTSK | |
| SCHEMBL1576452 | 0.94 | CTSK (0.40) | LIPEL3MBTL1GAACTSKCTSL | |
| SCHEMBL27760998 | 0.85 | EPHX1 (0.38) | LIPEL3MBTL1HPGDGAACTSK | |
| SCHEMBL28702168 | 0.85 | USP2 (0.39) | LIPEL3MBTL1GAACTSKCTSL | |
| SCHEMBL28942305 | 0.85 | EPHX1 (0.41) | LIPEL3MBTL1GAACTSKCTSL | |
| SCHEMBL7151133 | 0.83 | GNAI3 (0.38) | LIPEL3MBTL1GAACTSKCTSL | |
| SCHEMBL1430236 | 0.83 | LIPE (0.36) | LIPEL3MBTL1GAACTSKCTSL | |
| SCHEMBL5651167 | 0.81 | LIPE (0.39) | LIPEL3MBTL1GAACTSKCTSL | |
| SCHEMBL7449407 | 0.81 | KDM4E (0.42) | LIPEL3MBTL1GAACTSLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379575-B | Compounds and compositions for modulating EGFR activity | 诺华股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| WO-1998042656-A1 | NOVEL COMPOUNDS | CYTEL CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |