Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781178 | 0.90 | UBE2M (0.39) | UBE2MDCUN1D1MEN1KMT2ACYP2C19 | |
| SCHEMBL4776184 | 0.85 | DRD2 (0.42) | MEN1KMT2ACYP2C19LMNAPOLB | |
| SCHEMBL4780326 | 0.84 | CHRM4 (0.40) | UBE2MDCUN1D1DPP4DPP8DPP9 | |
| SCHEMBL4778369 | 0.84 | NOTUM (0.40) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL4776176 | 0.83 | FFAR4 (0.40) | FFAR4UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL4774338 | 0.81 | DRD2 (0.32) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4779536 | 0.81 | DRD2 (0.32) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4321609 | 0.80 | GRM5 (0.42) | MEN1KMT2ADPP4DPP8DPP9 | |
| SCHEMBL4775240 | 0.78 | MEN1 (0.41) | UBE2MDCUN1D1MEN1KMT2ADPP4 | |
| SCHEMBL4780332 | 0.78 | CHRM4 (0.38) | UBE2MDCUN1D1MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |