Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786240 | 0.83 | ALDH1A1 (0.63) | CES2CES1KEAP1ALDH1A1TP53 | |
| SCHEMBL106341 | 0.83 | HPGD (0.54) | CES2CES1ALDH1A1ALOX15HPGD | |
| SCHEMBL9834572 | 0.82 | CES2 (0.52) | CES2CES1KEAP1ALDH1A1ALOX15 | |
| SCHEMBL1785686 | 0.81 | ALDH1A1 (0.50) | CES2CES1KEAP1ALDH1A1HPGD | |
| SCHEMBL30954398 | 0.81 | CES2 (0.47) | CES2CES1KEAP1ALDH1A1ALOX15 | |
| SCHEMBL5884181 | 0.81 | CES2 (0.47) | CES2CES1KEAP1ALDH1A1HPGD | |
| SCHEMBL15471930 | 0.80 | ALDH1A1 (0.68) | CES2CES1KEAP1ALDH1A1HPGD | |
| SCHEMBL343535 | 0.80 | CES2 (0.68) | CES2CES1KEAP1ALDH1A1ALOX15 | |
| SCHEMBL20560592 | 0.78 | CES2 (0.39) | CES2CES1KEAP1ALDH1A1HPGD | |
| SCHEMBL11588418 | 0.78 | MAOB (0.49) | CES2CES1KEAP1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106966894-B | A kind of method of the pipe type continuously production chloro- 5- fluorobenzoyl chloride of 2,4- bis- | 浙江工业大学 | 2019-10-18 | — | — | CN | claimed |
| CN-209438289-U | For producing the tail gas water scrubber of the chloro- 5- fluorobenzoyl chloride of 2,4- bis- | 常州飞宇化工有限公司 | 2019-09-27 | — | — | CN | claimed |
| CN-109734581-A | A kind of preparation method of the chloro- 5- fluorobenzoyl chloride of fluoroquinolones intermediate 2,4- bis- | 和鼎（南京）医药技术有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-109553524-A | A kind of synthetic method of the chloro- 5- fluorobenzoyl chloride of 2,4- bis- | 浙江本立科技股份有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-107469828-B | A kind of nucleocapsid structure support type tungsten composite catalyst and its preparation method and application | 杭州师范大学 | 2018-12-11 | — | — | CN | claimed |
| CN-207667650-U | For the Friedel-Crafts reaction kettle in bis- chloro- 5- fluorobenzoyl chlorides preparation process of 2,4- | 常州飞宇化工有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-207641027-U | Rectifying column for bis- chloro- 5- fluorobenzoyl chlorides preparation process of 2,4- | 常州飞宇化工有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-207641479-U | Precipitation tower for bis- chloro- 5- fluorobenzoyl chlorides preparation process of 2,4- | 常州飞宇化工有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-207641058-U | Sedimentation kettle for bis- chloro- 5- fluorobenzoyl chlorides preparation process of 2,4- | 常州飞宇化工有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-108276331-A | A kind of preparation method and its process for refining of Norfloxacin | 山西云鹏制药有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-104292159-A | Preparation method of norfloxacin, ciprofloxacin and enrofloxacin | ZHEJIANG TONGFENG PHARMACEUTICAL & CHEMICAL CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-104211590-A | Preparation method of 2, 4-dichloro-fluorobenzoyl chloride | ZHEJIANG XIANFENG SCIENCE TECHNOLOGY CO LTD | 2014-12-17 | — | — | CN | claimed |
| CN-100556889-C | N-replaces-2,4-two chloro-5-fluorobenzamides and preparation thereof and application | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-11-04 | — | — | CN | claimed |
| CN-101033198-A | Compound of N-substituted-2,4-dichloro-5-fluorobenzamide, preparation and application thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-09-12 | — | — | CN | claimed |
| CN-1328238-C | Preparation of 2,4,5-trifluo-benzoic acid | LUYUAN PHARMACEUTICAL CO LTD D (CN) | 2007-07-25 | — | — | CN | claimed |
| CN-1746146-A | Preparation of 2,4,5-trifluo-benzoic acid | LUYUAN PHARMACEUTICAL CO LTD D (CN) | 2006-03-15 | — | — | CN | claimed |
| CN-1119324-C | 3-cyano-2, 4, 5-trifluorobenzoyl fluoride and intermediates for its preparation | BAYER AG (DE) | 2003-08-27 | — | — | CN | claimed |
| CN-1252789-A | 3-cyano-2, 4, 5-trifluorobenzoyl fluoride and intermediates for its preparation | BAYER AG (DE) | 2000-05-10 | — | — | CN | claimed |
| CN-85101686-B | 3-amino-2-benzoyl-acrylic acid derivative and a process for producing the same | 拜尔公司 | 1988-12-14 | — | — | CN | claimed |
| EP-0164619-A1 | 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them | BAYER AG (DE) | 1985-12-18 | — | — | EP | claimed |