Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325246 | 0.90 | PTGER4 (0.44) | PTGER4AOC3LMNA | |
| SCHEMBL4780075 | 0.80 | PTGER4 (0.50) | PTGER4CNR2HDAC6PSMD14LMNA | |
| SCHEMBL689666 | 0.75 | CYP19A1 (0.64) | PTGER4HDAC6PSMD14LMNACYP19A1 | |
| SCHEMBL4794458 | 0.75 | EP300 (0.39) | CNR2AOC3SMO | |
| SCHEMBL840830 | 0.74 | ALDH1A1 (0.55) | CNR2AOC3LMNAALDH1A3 | |
| SCHEMBL28392221 | 0.74 | P2RX4 (0.61) | PTGER4HDAC6PSMD14LMNACYP19A1 | |
| SCHEMBL8156486 | 0.74 | PTGER4 (0.55) | PTGER4HDAC6PSMD14LMNACYP19A1 | |
| SCHEMBL4780793 | 0.74 | PTGER4 (0.55) | PTGER4HDAC6PSMD14LMNACYP19A1 | |
| SCHEMBL4793098 | 0.73 | CYP11B1 (0.44) | PTGER4CNR2HDAC6PSMD14LMNA | |
| SCHEMBL1735017 | 0.72 | TRIM24 (0.53) | CNR2AOC3LMNAALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |