Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775757 | 0.90 | PTGER4 (0.46) | PTGER4AOC3LMNA | |
| SCHEMBL4780075 | 0.79 | PTGER4 (0.50) | PTGER4KDM4EMAPTMEN1KMT2A | |
| SCHEMBL30287647 | 0.75 | ALDH1A1 (0.55) | CYP11B1CYP11B2KDM4EMAPTMEN1 | |
| SCHEMBL1124372 | 0.75 | ALDH1A1 (0.55) | CYP11B1CYP11B2KDM4EMAPTMEN1 | |
| SCHEMBL689666 | 0.74 | CYP19A1 (0.64) | PTGER4KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8156486 | 0.72 | PTGER4 (0.55) | PTGER4KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28392221 | 0.72 | P2RX4 (0.61) | PTGER4KDM4ETSHRMEN1KMT2A | |
| SCHEMBL4780793 | 0.72 | PTGER4 (0.55) | PTGER4KDM4EMAPTHTTLMNA | |
| SCHEMBL4793098 | 0.72 | CYP11B1 (0.44) | PTGER4CYP11B1CYP11B2KDM4EMAPT | |
| SCHEMBL4779161 | 0.70 | PTGER4 (0.48) | PTGER4CYP11B1KDM4ENPY5RHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |