Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775900 | 1.00 | MBTD1 (0.39) | MBTD1L3MBTL3DRD2DRD4DRD3 | |
| SCHEMBL4780447 | 0.86 | OPRD1 (0.41) | MBTD1L3MBTL3DRD2DRD4DRD3 | |
| SCHEMBL1795969 | 0.85 | LMNA (0.43) | PRCP | |
| SCHEMBL1795967 | 0.85 | LMNA (0.43) | PRCP | |
| SCHEMBL22557476 | 0.83 | OPRD1 (0.49) | — | |
| SCHEMBL22557475 | 0.83 | OPRD1 (0.49) | — | |
| SCHEMBL4779720 | 0.83 | OPRD1 (0.49) | — | |
| SCHEMBL4779712 | 0.83 | OPRD1 (0.49) | — | |
| SCHEMBL3517323 | 0.80 | SLC6A3 (0.46) | — | |
| SCHEMBL3514322 | 0.80 | SLC6A3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |