Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775907 | 0.86 | MBTD1 (0.39) | MBTD1L3MBTL3PRCPDRD2DRD4 | |
| SCHEMBL4775900 | 0.86 | MBTD1 (0.39) | MBTD1L3MBTL3PRCPDRD2DRD4 | |
| SCHEMBL1797557 | 0.85 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL3515953 | 0.85 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL1797560 | 0.85 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL4781736 | 0.85 | OPRD1 (0.43) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4792274 | 0.83 | OPRD1 (0.49) | OPRD1OPRM1 | |
| SCHEMBL4778028 | 0.80 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4776163 | 0.80 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL3516176 | 0.80 | SLC6A3 (0.46) | OPRD1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |