Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781138 | 0.83 | S1PR1 (0.39) | SIGMAR1CNR1 | |
| SCHEMBL4780934 | 0.76 | DHODH (0.40) | KDM4ENPC1RAB9ASMN1; SMN2KCNH2 | |
| SCHEMBL4776462 | 0.76 | CTSK (0.40) | SIGMAR1MEN1KMT2ACNR1ACHE | |
| SCHEMBL4848577 | 0.71 | SIGMAR1 (0.38) | SIGMAR1LMNACYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL4246716 | 0.69 | DPP7 (0.60) | TNKS2POLBLMNACYP3A4CYP2C19 | |
| SCHEMBL39631 | 0.69 | DPP7 (0.73) | POLBSIGMAR1LMNAMEN1KMT2A | |
| SCHEMBL4774621 | 0.68 | DHODH (0.41) | KDM4ENPC1RAB9ASMN1; SMN2KCNH2 | |
| SCHEMBL4774798 | 0.68 | NOS3 (0.42) | MEN1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5758788 | 0.68 | DPP7 (0.71) | POLBSIGMAR1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7000083 | 0.68 | DPP7 (0.71) | POLBSIGMAR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |