Sugi Predict

Sugi Predict / Compounds / SCHEMBL4777259

SCHEMBL4777259

SCHEMBL4777259

CC(=O)N[C@@H](CSC(C)=O)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ FCER2 P06734 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ CPB2 Q96IY4 1/20 0.35
▸ CHRM2 P08172 1/20 0.35
▸ CHRM4 P08173 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ PAM P19021 1/20 0.34
▸ MME P08473 2/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.33
▸ ACE P12821 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10564990 0.88 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL11112209 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL11113212 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL20830614 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL12807816 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL9802984 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL20850498 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
SCHEMBL20830443 0.83 MAPT (0.42) MAPTKDM4ETHRBALOX15NFKB1
Dacisteine SCHEMBL2402188 0.82 MAPT (0.55) MAPTKDM4ETHRBALOX15NFKB1
Dacisteine SCHEMBL1814125 0.82 MAPT (0.55) MAPTKDM4ETHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1231886-A4 TOPICAL SKIN COMPOSITION ACCESS BUSINESS GROUP INT LLC (US) 2005-10-12 — — EP claimed
US-20030095959-A1 Topical skin composition ACCESS BUSINESS GROUP INTERNATIONAL LLC. 2003-05-22 — — US claimed
EP-1231886-A1 TOPICAL SKIN COMPOSITION Alticor Inc. (US) 2002-08-21 — — EP claimed
WO-2001037788-A1 TOPICAL SKIN COMPOSITION ALTICOR INC. (US) 2001-05-31 — — WO claimed
WO-1994004129-A2 COSMETIC AND DERMATOLOGICAL SUNSCREEN COMPOSITIONS CONTAINING THIOLS AND/OR THIOL DERIVATES BEIERSDORF AG (DE) 1994-03-03 — — WO claimed
US-20080124409-A1 Topical Skin Compositions, Their Preparation, and Their Use ACCESS BUSINESS GROUP INTERNATIONAL LLC 2008-05-29 — — US disclosed
US-20080081034-A1 Topical Skin Compositions, Their Preparation, and Their Use ACCESS BUSINESS GROUP INTERNATIONAL LLC 2008-04-03 — — US disclosed
US-20080081082-A1 Topical Skin Compositions, Their Preparation, and Their Use ACCESS BUSINES GROUP INTERNATIONAL LLC 2008-04-03 — — US disclosed
WO-2008016842-A1 TOPICAL SKIN COMPOSITIONS, THEIR PREPARATION, AND THEIR USE ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2008-02-07 — — WO disclosed
WO-2008016838-A1 TOPICAL SKIN COMPOSITIONS, THEIR PREPARATION AND THEIR USE ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2008-02-07 — — WO disclosed
US-20070003536-A1 Topical skin compositions, their preparation, and their use ACCESS BUSINESS GROUP INTERNATIONAL LLC 2007-01-04 — — US disclosed
EP-1231886-A4 TOPICAL SKIN COMPOSITION ACCESS BUSINESS GROUP INT LLC (US) 2005-10-12 — — EP disclosed
US-20030095959-A1 Topical skin composition ACCESS BUSINESS GROUP INTERNATIONAL LLC. 2003-05-22 — — US disclosed
EP-1231886-A1 TOPICAL SKIN COMPOSITION Alticor Inc. (US) 2002-08-21 — — EP disclosed
WO-2001037788-A1 TOPICAL SKIN COMPOSITION ALTICOR INC. (US) 2001-05-31 — — WO disclosed
EP-0656774-B1 COSMETIC AND DERMATOLOGICAL SUNSCREEN COMPOSITIONS CONTAINING THIOLS AND/OR THIOL DERIVATES BEIERSDORF AG (DE) 1997-01-22 — — EP disclosed
EP-0656774-A1 COSMETIC AND DERMATOLOGICAL SUNSCREEN COMPOSITIONS CONTAINING THIOLS AND/OR THIOL DERIVATES. BEIERSDORF AG (DE) 1995-06-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081034-A1 Topical Skin Compositions, Their Preparation, and Their Use COL14A1, MMP8, MMP1 MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885
US-20080124409-A1 Topical Skin Compositions, Their Preparation, and Their Use COL14A1, MMP8, MMP1 MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885
US-20030095959-A1 Topical skin composition CUTA, S100A4, KRT18 MAPT 1787/4885KDM4E 4634/4885THRB 3415/4885
US-20070003536-A1 Topical skin compositions, their preparation, and their use COL14A1, MMP8, MMP1 MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885
US-20080081082-A1 Topical Skin Compositions, Their Preparation, and Their Use COL14A1, MMP8, MMP1 MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.