Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780097 | 0.94 | KIF11 (0.41) | KIF11KCNH2HRH3ACHEP2RX7 | |
| SCHEMBL4773635 | 0.88 | KCNH2 (0.40) | KIF11KCNH2 | |
| SCHEMBL4775780 | 0.88 | KCNH2 (0.40) | KIF11KCNH2 | |
| SCHEMBL4752782 | 0.88 | KIF11 (0.42) | KIF11 | |
| SCHEMBL4752779 | 0.88 | KIF11 (0.42) | KIF11 | |
| SCHEMBL4780721 | 0.87 | KIF11 (0.46) | KIF11KCNH2 | |
| SCHEMBL4776368 | 0.87 | KIF11 (0.46) | KIF11KCNH2 | |
| SCHEMBL4025178 | 0.86 | KIF11 (0.45) | KIF11KCNH2HRH3ACHEGRIN2B | |
| SCHEMBL4776377 | 0.85 | KCNH2 (0.42) | KIF11KCNH2 | |
| SCHEMBL4780207 | 0.85 | L3MBTL1 (0.37) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |