Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 8/20 | 0.38 |
| ▸ | KCNK10 | P57789 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490024 | 0.73 | L3MBTL1 (0.42) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6497474 | 0.73 | PLK1 (0.61) | KIF11TRPV1PTPRZ1EPHX2NR1H4 | |
| SCHEMBL5481193 | 0.70 | ROCK2 (0.30) | — | |
| SCHEMBL20328053 | 0.70 | MMP2 (0.36) | KIF11TRPV1PTPRZ1ALDH1A1PTPN1 | |
| SCHEMBL4726846 | 0.70 | KIF11 (0.51) | KIF11TRPV1PTPRZ1ALDH1A1KDM4E | |
| SCHEMBL11755915 | 0.69 | ALDH1A1 (0.52) | KIF11PTPRZ1ALDH1A1KDM4ETDP1 | |
| SCHEMBL11731759 | 0.69 | KIF11 (0.58) | KIF11TRPV1ALDH1A1NPC1RAB9A | |
| SCHEMBL4149723 | 0.69 | TSHR (0.38) | KIF11TRPV1PTPRZ1ALDH1A1EPHX2 | |
| SCHEMBL11777920 | 0.67 | KIF11 (0.51) | KIF11TRPV1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL11778655 | 0.67 | TRPV1 (0.57) | KIF11TRPV1PTPRZ1ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |