Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154142 | 0.79 | ACHE (0.37) | ACHEEPHX1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2309682 | 0.79 | EGLN1 (0.41) | FAAHACHEEPHX1CHRNB2CHRNB4 | |
| SCHEMBL21708618 | 0.76 | LMNA (0.37) | FAAHCNR1CNR2 | |
| SCHEMBL6615472 | 0.75 | ALOX15 (0.41) | FAAHACHEEPHX1CHRNB2CHRNB4 | |
| SCHEMBL17748720 | 0.74 | HDAC7 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4CTSK | |
| SCHEMBL11969584 | 0.74 | EPHX1 (0.59) | ACHEEPHX1 | |
| SCHEMBL11969386 | 0.74 | EPHX1 (0.55) | ACHEEPHX1 | |
| SCHEMBL1276782 | 0.73 | DPP7 (0.45) | EPHX1 | |
| SCHEMBL1933764 | 0.73 | ALDH1A1 (0.41) | FAAHCNR1CNR2HDAC7HDAC8 | |
| SCHEMBL9989327 | 0.73 | HDAC7 (0.35) | CTSKHDAC7HDAC8HDAC6HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078116-A9 | P38 INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC (US) | 2008-09-12 | — | — | WO | disclosed |