Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 7/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | MMP14 | P50281 | 5/20 | 0.49 |
| ▸ | MMP3 | P08254 | 4/20 | 0.49 |
| ▸ | MMP8 | P22894 | 4/20 | 0.49 |
| ▸ | MMP13 | P45452 | 4/20 | 0.49 |
| ▸ | MMP16 | P51512 | 3/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792747 | 0.75 | PKM (0.58) | ADAMTS4MMP2MMP9MMP14MMP3 | |
| SCHEMBL25437664 | 0.73 | HSD11B1 (0.51) | PTGESKDM4EMAPTKMT2A | |
| SCHEMBL4073854 | 0.72 | LMNA (0.63) | ADAMTS4PKMNPC1RAB9AKDM4E | |
| SCHEMBL15705805 | 0.72 | MMP1 (0.51) | ADAMTS4MMP2MMP9MMP14MMP3 | |
| Biphenyl SCHEMBL6746212 | 0.72 | ALDH1A1 (0.48) | ADAMTS4MMP2MMP9MMP14MMP3 | |
| SCHEMBL15705623 | 0.71 | DAGLA (0.58) | MMP2MMP9MMP14MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL28477859 | 0.71 | LMNA (0.61) | ADAMTS4PKMNPC1RAB9AKDM4E | |
| SCHEMBL15705773 | 0.70 | MMP1 (0.54) | ADAMTS4MMP2MMP9MMP14MMP3 | |
| SCHEMBL8761424 | 0.69 | CA1 (0.54) | MMP2MMP14PKMMMP7 | |
| SCHEMBL6794824 | 0.68 | CA12 (0.73) | ADAMTS4PKMKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024784-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | ARRAY BIOPHARMA, INC. (US) | 2008-02-28 | — | — | WO | disclosed |