Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 4/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 4/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL4734054 | 0.98 | LMNA (0.50) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL735933 | 0.95 | ACHE (0.58) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL1308696 | 0.89 | LMNA (0.46) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL1718753 | 0.86 | LMNA (0.52) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL27542416 | 0.80 | LMNA (0.58) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL9640920 | 0.80 | LMNA (0.58) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL9640890 | 0.80 | LMNA (0.58) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL190031 | 0.80 | LMNA (0.58) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL3710402 | 0.80 | LMNA (0.37) | LMNAACHETSHRALOX12ORAI1 | |
| Toluene SCHEMBL9672173 | 0.79 | ACHE (0.85) | LMNAACHETSHRALOX12CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008015196-A1 | 5-,7-BIS-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES | NYCOMED GMBH (DE) | 2008-02-07 | — | — | WO | disclosed |
| US-20060194969-A1 | 4-Substituted benzimidazoles and their uses as inhibitors of gastric secretion | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-1575924-A1 | 4-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | ALTANA Pharma AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004054984-A1 | 4-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | ALTANA PHARMA AG (DE) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194969-A1 | 4-Substituted benzimidazoles and their uses as inhibitors of gastric secretion | GIPR, VIP, SI | LMNA 4583/4885ACHE 675/4885TSHR 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.