Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 5/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 5/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL4779666 | 0.95 | LMNA (0.52) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL4734054 | 0.93 | LMNA (0.50) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL1308696 | 0.89 | LMNA (0.46) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL9640890 | 0.84 | LMNA (0.58) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL9640920 | 0.84 | LMNA (0.58) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL190031 | 0.84 | LMNA (0.58) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL27542416 | 0.84 | LMNA (0.58) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL5070511 | 0.82 | LMNA (0.55) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL7754116 | 0.82 | LMNA (0.55) | ACHETSHRLMNAALOX12ORAI1 | |
| Toluene SCHEMBL7754119 | 0.82 | LMNA (0.55) | ACHETSHRLMNAALOX12ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043643-B2 | Vaccine against klebsiella pneumoniae | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-07-23 | — | — | US | disclosed |
| WO-2024121280-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-13 | — | — | WO | disclosed |
| US-11981685-B2 | Bicyclic heterocyclyl derivatives as IRAK4 inhibitors | AURIGENE ONCOLOGY LIMITED (IN) | 2024-05-14 | — | — | US | disclosed |
| US-20230265103-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC | 2023-08-24 | — | — | US | disclosed |
| US-11691987-B2 | Bicyclic heterocyclyl derivatives as IRAK4 inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-07-04 | — | — | US | disclosed |
| US-20230122752-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-04-20 | — | — | US | disclosed |
| WO-2023036976-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-03-16 | — | — | WO | disclosed |
| US-20230045939-A1 | STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-02-16 | — | — | US | disclosed |
| US-11479574-B2 | Vaccine against Klebsiella pneumoniae | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-10-25 | — | — | US | disclosed |
| US-11342507-B2 | Coating composition comprising compound, and organic light emitting device comprising same | LG CHEM, LTD. | 2022-05-24 | — | — | US | disclosed |
| US-4704460-A | LEUKOCYTES IN URINE | MILES LABORATORIES, INC. (US) | 1987-11-03 | — | — | US | disclosed |
| US-4657855-A | DIP-AND-READ, UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4645842-A | DETECTING LEUKOCYTES TO INDICATE KIDNEY OR UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-02-24 | — | — | US | disclosed |
| US-4637979-A | Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent | MILES LABORATORIES, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0158226-A2 | Method of synthesizing esters | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0158204-A2 | Composition and test device for determining the presence of leukocytes, containing a zwitterion coupling agent | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0157327-A2 | Novel compounds for detecting the presence of hydrolytic analytes in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0157326-A2 | Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| US-4526933-A | Polymeric active methylene compounds, their preparation and their use in azo polymers | DYNAPOL (US) | 1985-07-02 | — | — | US | disclosed |
| US-4489197-A | SUPPLYING DRUGS TO LOWER BOWEL | DYNAPOL (US) | 1984-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691987-B2 | Bicyclic heterocyclyl derivatives as IRAK4 inhibitors | IRAK4, IRAK3, IRAK1 | ACHE 3998/4885TSHR 4367/4885LMNA 1021/4885 |
| US-20230045939-A1 | STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE | DDOST, SI, CD4 | ACHE 2920/4885TSHR 3529/4885LMNA 4672/4885 |
| US-11981685-B2 | Bicyclic heterocyclyl derivatives as IRAK4 inhibitors | IRAK4, IRAK3, IRAK1 | ACHE 3917/4885TSHR 4307/4885LMNA 863/4885 |
| US-20230265103-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | PIKFYVE, PIK3CD, PIK3R5 | ACHE 2468/4885TSHR 3316/4885LMNA 4521/4885 |
| US-11479574-B2 | Vaccine against Klebsiella pneumoniae | SLC11A2, OSTC, STT3A | ACHE 1214/4885TSHR 4421/4885LMNA 4373/4885 |
| US-11342507-B2 | Coating composition comprising compound, and organic light emitting device comprising same | CRY1, OR10J3, COPB2 | ACHE 520/4885TSHR 4707/4885LMNA 2562/4885 |
| US-12043643-B2 | Vaccine against klebsiella pneumoniae | SLC11A2, OSTC, STT3A | ACHE 1214/4885TSHR 4421/4885LMNA 4373/4885 |
| US-20230122752-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | SLC11A2, OSTC, STT3A | ACHE 1214/4885TSHR 4421/4885LMNA 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.