Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782108 | 0.89 | ALDH1A1 (0.42) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL6361627 | 0.76 | P2RX7 (0.60) | ALDH1A1HTTP2RX7 | |
| SCHEMBL13232458 | 0.75 | AGTR1 (0.47) | — | |
| SCHEMBL21385186 | 0.75 | ALDH1A1 (0.43) | ALDH1A1POLBHTTP2RX7DGAT1 | |
| SCHEMBL12098938 | 0.75 | ERCC5 (0.50) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL7670834 | 0.75 | AGTR1 (0.39) | ALDH1A1HTTP2RX7 | |
| SCHEMBL23910055 | 0.73 | DGAT1 (0.34) | ALDH1A1POLBHTTDGAT1 | |
| SCHEMBL12173141 | 0.73 | P2RX7 (0.56) | ALDH1A1HTTP2RX7HSD11B1 | |
| SCHEMBL9199814 | 0.73 | MAPK8 (0.42) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL30750461 | 0.72 | ALDH1A1 (0.43) | ALDH1A1POLBHTTP2RX7HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012852-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS | S.I.M.S. S.r.l. - SOCIETÀ ITALIANA MEDICINALI SCANDICCI (IT) | 2008-01-31 | — | — | WO | disclosed |