Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30750461 | 0.79 | ALDH1A1 (0.43) | ALDH1A1POLBHTT | |
| SCHEMBL20299197 | 0.77 | LMNA (0.40) | DGAT1ALDH1A1HTT | |
| SCHEMBL23113033 | 0.75 | DGAT1 (0.33) | DGAT1ALDH1A1POLBHTT | |
| SCHEMBL21385186 | 0.74 | ALDH1A1 (0.43) | DGAT1ALDH1A1POLBHTT | |
| SCHEMBL4782108 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLBHTT | |
| SCHEMBL4780224 | 0.73 | ALDH1A1 (0.39) | DGAT1ALDH1A1POLBHTT | |
| SCHEMBL9954569 | 0.73 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL1060454 | 0.71 | ALDH1A1 (0.37) | DGAT1ALDH1A1POLBHTT | |
| SCHEMBL2144514 | 0.70 | NPC1 (0.40) | DGAT1ALDH1A1HTT | |
| SCHEMBL20401617 | 0.70 | RAB9A (0.35) | DGAT1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | DGAT1 2236/4885ALDH1A1 485/4885POLB 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.