Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582569 | 0.88 | LMNA (0.43) | LMNAALDH1A1HPGDSMN1; SMN2PKM | |
| SCHEMBL4797387 | 0.78 | ACHE (0.46) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL14273445 | 0.74 | ALDH1A1 (0.52) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL4778439 | 0.73 | MAOA (0.51) | MAOAKMT2AMAPTMEN1LMNA | |
| SCHEMBL4780631 | 0.71 | MAOA (0.49) | MAOAKMT2AMAPTMEN1LMNA | |
| SCHEMBL4782134 | 0.69 | MAP3K7 (0.56) | MAOAKMT2AMAPTMEN1TTR | |
| SCHEMBL4795380 | 0.69 | MAPT (0.55) | MAOAKMT2AMAPTMEN1LMNA | |
| SCHEMBL4795882 | 0.69 | MAP3K7 (0.56) | MAOAKMT2AMAPTMEN1LMNA | |
| SCHEMBL4782629 | 0.69 | MAOA (0.46) | MAOAKMT2AMAPTMEN1LMNA | |
| Anthrarufin SCHEMBL25355428 | 0.67 | MAOA (0.86) | MAOAKMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015265-A1 | ANTHRACEN DERIVATIVES AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOROUS DISEASES | ÆTERNA ZENTARIS GMBH (DE) | 2008-02-07 | — | — | WO | claimed |
| WO-2008015265-A1 | ANTHRACEN DERIVATIVES AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOROUS DISEASES | ÆTERNA ZENTARIS GMBH (DE) | 2008-02-07 | — | — | WO | disclosed |